MEF2D antibody (AA 431-521)

Catalog No. ABIN7268733

Product Details anti-MEF2D Antibody

Target: MEF2D (Myocyte Enhancer Factor 2D (MEF2D))

Binding Specificity: AA 431-521

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEF2D antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: MEF2D Rabbit pAb

Sequence: TTHPHISIKS EPVSPSRERS PAPPPPAVFP AARPEPGDGL SSPAGGSYET GDRDDGRGDF GPTLGLLRPA PEPEAEGSAV KRMRLDTWTL K

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 431-521 of human MEF2D (NP_005911.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MEF2D

Target: MEF2D (Myocyte Enhancer Factor 2D (MEF2D))

Alternative Name: MEF2D (MEF2D Products)

Synonyms: sl1 antibody, sl-1 antibody, XMEF2D antibody, MGC145245 antibody, C80750 antibody, myocyte enhancer factor 2D antibody, MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) antibody, mef2d antibody, MEF2D antibody, Mef2d antibody

Background: This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants.,MEF2D,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,ErbB-HER Signaling Pathway,MAPK-P38 Signaling Pathway,Endocrine & Metabolism,AMPK Signaling Pathway,Neuroscience,Cardiovascular,Heart,Cardiogenesis,Hypertrophy,MEF2D

Molecular Weight: 49kDa/50kDa/55kDa/56kDa

Gene ID: 4209

UniProt: Q14814