MRPL43 antibody (AA 80-155)

Catalog No. ABIN7268573

Product Details anti-MRPL43 Antibody

Target: MRPL43 (Mitochondrial Ribosomal Protein L43 (MRPL43))

Binding Specificity: AA 80-155

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL43 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: MRPL43 Rabbit pAb

Sequence: LNGAVREESI HCKSVEEIST LVQKLADQSG LDVIRIRKPF HTDNPSIQGQ WHPFTNKPTT FRGLRPREVQ DPAPAQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 80-155 of human MRPL43 (NP_789762.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MRPL43

Target: MRPL43 (Mitochondrial Ribosomal Protein L43 (MRPL43))

Alternative Name: MRPL43 (MRPL43 Products)

Synonyms: bMRP36a antibody, 4930442D21Rik antibody, mitochondrial ribosomal protein L43 antibody, MRPL43 antibody, Mrpl43 antibody

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for a semaphorin class 4 protein (SEMA4G) overlap at map location 10q24.31 and are transcribed in opposite directions. Sequence analysis identified multiple transcript variants encoding at least four different protein isoforms. [provided by RefSeq, Jul 2008],L43mt,MRP-L43,bMRP36a,MRPL43,Epigenetics & Nuclear Signaling,RNA Binding,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Mitochondrial translation,MRPL43

Gene ID: 84545

UniProt: Q8N983