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MCM7 antibody

MCM7 Reactivity: Human WB, IHC, IF, IP Host: Rabbit Monoclonal unconjugated
Catalog No. ABIN7268544
  • Target See all MCM7 Antibodies
    MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
    Reactivity
    • 116
    • 31
    • 25
    • 11
    • 10
    • 10
    • 9
    • 9
    • 4
    • 2
    • 1
    Human
    Host
    • 76
    • 38
    • 2
    Rabbit
    Clonality
    • 73
    • 43
    Monoclonal
    Conjugate
    • 74
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MCM7 antibody is un-conjugated
    Application
    • 77
    • 32
    • 30
    • 22
    • 21
    • 20
    • 13
    • 13
    • 13
    • 12
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    Purpose
    MCM7 Rabbit mAb
    Cross-Reactivity
    Human, Rat
    Characteristics
    Monoclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    A synthesized peptide derived from human MCM7
    Isotype
    IgG
    Top Product
    Discover our top product MCM7 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
    Alternative Name
    MCM7 (MCM7 Products)
    Background
    The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],CDC47, MCM2, P1.1-MCM3, P1CDC47, P85MCM, PNAS146, PPP1R104,Epigenetics & Nuclear Signaling,MCM7
    Molecular Weight
    81kDa
    Gene ID
    4176
    UniProt
    P33993
    Pathways
    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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