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MCM2 antibody

MCM2 Reactivity: Human WB, IHC, IF Host: Rabbit Monoclonal unconjugated
Catalog No. ABIN7268538
  • Target See all MCM2 Antibodies
    MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))
    Reactivity
    • 118
    • 64
    • 22
    • 10
    • 10
    • 9
    • 8
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Human
    Host
    • 118
    • 11
    • 2
    • 1
    Rabbit
    Clonality
    • 115
    • 17
    Monoclonal
    Conjugate
    • 74
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This MCM2 antibody is un-conjugated
    Application
    • 77
    • 43
    • 40
    • 28
    • 27
    • 26
    • 21
    • 20
    • 13
    • 10
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Purpose
    MCM2 Rabbit mAb
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Monoclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human MCM2.
    Isotype
    IgG
    Top Product
    Discover our top product MCM2 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))
    Alternative Name
    MCM2 (MCM2 Products)
    Background
    The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.,MCM2,BM28,CCNL1,CDCL1,D3S3194,DFNA70,MITOTIN,cdc19,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Stem Cells,MCM2
    Molecular Weight
    101kDa
    Gene ID
    4171
    UniProt
    P49736
    Pathways
    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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