MMADHC antibody (AA 1-296)

Catalog No. ABIN7268495

Product Details anti-MMADHC Antibody

Target: MMADHC (Methylmalonic Aciduria (Cobalamin Deficiency) CblD Type, with Homocystinuria (MMADHC))

Binding Specificity: AA 1-296

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMADHC antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: MMADHC Rabbit pAb

Sequence: MANVLCNRAR LVSYLPGFCS LVKRVVNPKA FSTAGSSGSD ESHVAAAPPD ICSRTVWPDE TMGPFGPQDQ RFQLPGNIGF DCHLNGTASQ KKSLVHKTLP DVLAEPLSSE RHEFVMAQYV NEFQGNDAPV EQEINSAETY FESARVECAI QTCPELLRKD FESLFPEVAN GKLMILTVTQ KTKNDMTVWS EEVEIEREVL LEKFINGAKE ICYALRAEGY WADFIDPSSG LAFFGPYTNN TLFETDERYR HLGFSVDDLG CCKVIRHSLW GTHVVVGSIF TNATPDSHIM KKLSGN

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-296 of human MMADHC (NP_056517.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MMADHC

Target: MMADHC (Methylmalonic Aciduria (Cobalamin Deficiency) CblD Type, with Homocystinuria (MMADHC))

Alternative Name: MMADHC (MMADHC Products)

Synonyms: C2orf25 antibody, CL25022 antibody, cblD antibody, 2010311D03Rik antibody, AI314967 antibody, RGD1303272 antibody, methylmalonic aciduria and homocystinuria, cblD type antibody, methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria antibody, MMADHC antibody, Mmadhc antibody

Background: This gene encodes a mitochondrial protein that is involved in an early step of vitamin B12 metabolism. Vitamin B12 (cobalamin) is essential for normal development and survival in humans. Mutations in this gene cause methylmalonic aciduria and homocystinuria type cblD (MMADHC), a disorder of cobalamin metabolism that is characterized by decreased levels of the coenzymes adenosylcobalamin and methylcobalamin. Pseudogenes have been identified on chromosomes 11 and X.,MMADHC,C2orf25,CL25022,cblD,cblD type,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,MMADHC

Molecular Weight: 32kDa

Gene ID: 27249

UniProt: Q9H3L0