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- Target See all MC1 Receptor (MC1R) Antibodies
- MC1 Receptor (MC1R) (Melanocortin 1 Receptor (MC1R))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This MC1 Receptor antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- MC1 Receptor Rabbit mAb
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Monoclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- A synthesized peptide derived from human MC1 Receptor
- Isotype
- IgG
- Top Product
- Discover our top product MC1R Primary Antibody
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anti-Melanocortin 1 Receptor (MC1R) (AA 1-37) antibody
MC1R Reactivity: Human ELISA, WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) (AA 271-317) antibodyMC1R Reactivity: Human, Mouse ELISA, WB, IF (cc), IF (p), FACS, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) (C-Term) antibodyMC1R Reactivity: Human, Mouse, Rat ELISA, WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) (C-Term) antibodyMC1R Reactivity: Human WB, IF, IHC (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) (3rd Intracellular Loop), (AA 217-232) antibodyMC1R Reactivity: Human, Rat WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) (Cytoplasmic Domain) antibodyMC1R Reactivity: Human, Monkey IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) (C-Term) antibodyMC1R Reactivity: Human ELISA, WB, IF Host: Rabbit Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) (AA 205-232) antibodyMC1R Reactivity: Human WB Host: Mouse Monoclonal 578CT6-2-3 unconjugated
anti-Melanocortin 1 Receptor (MC1R) (AA 271-317) antibody (AbBy Fluor® 488)MC1R Reactivity: Human, Mouse WB, IF (cc), IF (p), FACS Host: Rabbit Polyclonal AbBy Fluor® 488
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- Application Notes
- WB,1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- MC1 Receptor (MC1R) (Melanocortin 1 Receptor (MC1R))
- Alternative Name
- MC1R (MC1R Products)
- Background
- This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis. This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer. Over 30 variant alleles have been identified which correlate with skin and hair color, providing evidence that this gene is an important component in determining normal human pigment variation. [provided by RefSeq, Jul 2008],CMM5, MSH-R, SHEP2,Endocrine & Metabolism,G protein signaling,G protein signaling_G-Protein-Coupled Receptors(GPCR),Neuroscience,Signal Transduction,MC1R
- Molecular Weight
- 35kDa
- Gene ID
- 4157
- UniProt
- Q01726
- Pathways
- cAMP Metabolic Process, Feeding Behaviour
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