MAD4 antibody, MST149 antibody, MSTP149 antibody, bHLHc12 antibody, xmad4 antibody, mst149 antibody, bhlhc12 antibody, mstp149 antibody, MGC84841 antibody, MXD4 antibody, 2810410A03Rik antibody, Mad4 antibody, MAX dimerization protein 4 antibody, Max dimerization protein 4 antibody, MAX dimerization protein 4 S homeolog antibody, microRNA 4800 antibody, MXD4 antibody, Mxd4 antibody, mxd4.S antibody, MIR4800 antibody, mxd4 antibody
Background
This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.,MXD4,MAD4,MST149,MSTP149,bHLHc12,Epigenetics & Nuclear Signaling,Transcription Factors,MXD4