LILRB3 antibody (AA 400-500)

Catalog No. ABIN7268239

Product Details anti-LILRB3 Antibody

Target: LILRB3 (Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3))

Binding Specificity: AA 400-500

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LILRB3 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: LILRB3 Rabbit pAb

Sequence: RSSNPHLLSF PSEPLELMVS GHSGGSSLPP TGPPSTPGGP EDQPLNPPGS GPQNGLGRYL EVLIGVSVAF VLLLFLLLFL LLLRQRHSKH RTSDQRKTDF Q

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 400-500 of human LILRB3 (NP_001307889.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LILRB3

Target: LILRB3 (Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3))

Alternative Name: LILRB3 (LILRB3 Products)

Synonyms: CD85A antibody, HL9 antibody, ILT-5 antibody, ILT5 antibody, LILRA6 antibody, LIR-3 antibody, LIR3 antibody, PIRB antibody, Gp91 antibody, Lilrb3 antibody, PIR-B antibody, Pirb antibody, NILR-1 antibody, LILRB3 antibody, leukocyte immunoglobulin like receptor B3 antibody, paired Ig-like receptor B antibody, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 antibody, LILRB3 antibody, Pirb antibody

Background: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.,LILRB3,CD85A,HL9,ILT-5,ILT5,LILRA6,LIR-3,LIR3,PIR-B,PIRB,Immunology & Inflammation,CD markers,B Cell Receptor Signaling Pathway,LILRB3

Molecular Weight: 69kDa/71kDa

Gene ID: 11025

UniProt: O75022