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LGI1 antibody (AA 301-557)
LGI1
Reactivity: Human
WB, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-LGI1 Antibody
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Target
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LGI1
(Leucine-Rich, Glioma Inactivated 1 (LGI1))
Binding Specificity
All epitopes for LGI1 antibodies
AA 301-557
Reactivity
All reactivities for LGI1 antibodies
Human
Host
All hosts for LGI1 antibodies
Rabbit
Clonality
All clonalities for LGI1 antibodies
Polyclonal
Conjugate
All conjugates for LGI1 antibodies
This LGI1 antibody is un-conjugated
Application
All applications for LGI1 antibodies
Western Blotting (WB), Immunofluorescence (IF)
Purpose
LGI1 Rabbit pAb
Sequence
QLFGGSHIYK RDSFANKFIK IQDIEILKIR KPNDIETFKI ENNWYFVVAD SSKAGFTTIY KWNGNGFYSH QSLHAWYRDT DVEYLEIVRT PQTLRTPHLI LSSSSQRPVI YQWNKATQLF TNQTDIPNME DVYAVKHFSV KGDVYICLTR FIGDSKVMKW GGSSFQDIQR MPSRGSMVFQ PLQINNYQYA ILGSDYSFTQ VYNWDAEKAK FVKFQELNVQ APRSFTHVSI NKRNFLFASS FKGNTQIYKH VIVDLSA
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 301-557 of human LGI1 (NP_005088.1).
Isotype
IgG
Top Product
Discover our top product LGI1 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IF,1:50 - 1:100
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for LGI1
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Target
LGI1
(Leucine-Rich, Glioma Inactivated 1 (LGI1))
Alternative Name
LGI1 (LGI1 Products )
Synonyms
ADLTE antibody, ADPAEF antibody, ADPEAF antibody, EPITEMPIN antibody, EPT antibody, ETL1 antibody, IB1099 antibody, BB130740 antibody, MGC146600 antibody, LGIa antibody, fb78h12 antibody, wu:fb78h12 antibody, zgc:65886 antibody, leucine rich glioma inactivated 1 antibody, leucine-rich repeat LGI family, member 1 antibody, leucine-rich, glioma inactivated 1 antibody, leucine-rich, glioma inactivated 1b antibody, leucine-rich, glioma inactivated 1a antibody, LGI1 antibody, Lgi1 antibody, lgi1 antibody, lgi1b antibody, lgi1a antibody
Background
This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants.,LGI1,ADLTE,ADPAEF,ADPEAF,EPITEMPIN,EPT,ETL1,IB1099,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Wnt/β-Catenin Signaling Pathway,Neuroscience,Neurodegenerative Diseases,LGI1
Molecular Weight
33kDa/58kDa/63kDa
Gene ID
9211
UniProt
O95970
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