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LGI1 antibody (AA 301-557)

LGI1 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7268237
  • Target See all LGI1 Antibodies
    LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))
    Binding Specificity
    • 19
    • 15
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-557
    Reactivity
    • 43
    • 24
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 26
    • 22
    Rabbit
    Clonality
    • 27
    • 21
    Polyclonal
    Conjugate
    • 18
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LGI1 antibody is un-conjugated
    Application
    • 47
    • 22
    • 15
    • 13
    • 13
    • 13
    • 13
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Purpose
    LGI1 Rabbit pAb
    Sequence
    QLFGGSHIYK RDSFANKFIK IQDIEILKIR KPNDIETFKI ENNWYFVVAD SSKAGFTTIY KWNGNGFYSH QSLHAWYRDT DVEYLEIVRT PQTLRTPHLI LSSSSQRPVI YQWNKATQLF TNQTDIPNME DVYAVKHFSV KGDVYICLTR FIGDSKVMKW GGSSFQDIQR MPSRGSMVFQ PLQINNYQYA ILGSDYSFTQ VYNWDAEKAK FVKFQELNVQ APRSFTHVSI NKRNFLFASS FKGNTQIYKH VIVDLSA
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 301-557 of human LGI1 (NP_005088.1).
    Isotype
    IgG
    Top Product
    Discover our top product LGI1 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IF,1:50 - 1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))
    Alternative Name
    LGI1 (LGI1 Products)
    Synonyms
    ADLTE antibody, ADPAEF antibody, ADPEAF antibody, EPITEMPIN antibody, EPT antibody, ETL1 antibody, IB1099 antibody, BB130740 antibody, MGC146600 antibody, LGIa antibody, fb78h12 antibody, wu:fb78h12 antibody, zgc:65886 antibody, leucine rich glioma inactivated 1 antibody, leucine-rich repeat LGI family, member 1 antibody, leucine-rich, glioma inactivated 1 antibody, leucine-rich, glioma inactivated 1b antibody, leucine-rich, glioma inactivated 1a antibody, LGI1 antibody, Lgi1 antibody, lgi1 antibody, lgi1b antibody, lgi1a antibody
    Background
    This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants.,LGI1,ADLTE,ADPAEF,ADPEAF,EPITEMPIN,EPT,ETL1,IB1099,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Wnt/β-Catenin Signaling Pathway,Neuroscience,Neurodegenerative Diseases,LGI1
    Molecular Weight
    33kDa/58kDa/63kDa
    Gene ID
    9211
    UniProt
    O95970
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