KBTBD8 antibody
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- Target See all KBTBD8 products
- KBTBD8 (Kelch Repeat and BTB (POZ) Domain Containing 8 (KBTBD8))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KBTBD8 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Purpose
- KBTBD8 Rabbit pAb
- Cross-Reactivity
- Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human KBTBD8.
- Isotype
- IgG
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- Application Notes
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- KBTBD8 (Kelch Repeat and BTB (POZ) Domain Containing 8 (KBTBD8))
- Alternative Name
- KBTBD8 (KBTBD8 Products)
- Synonyms
- TA-KRP antibody, AU040152 antibody, SSEC-51 antibody, SSEC51 antibody, Takrp antibody, mKIAA1842 antibody, RGD1563166 antibody, cb672 antibody, takrp antibody, wu:fc57a10 antibody, zgc:152950 antibody, kelch repeat and BTB domain containing 8 antibody, kelch repeat and BTB (POZ) domain containing 8 antibody, KBTBD8 antibody, Kbtbd8 antibody, kbtbd8 antibody
- Background
- Substrate-specific adapter of a BCR (BTB-CUL3-RBX1 E3 ubiquitin ligase complex that acts as a regulator of neural crest specification. The BCR(KBTBD8 complex acts by mediating monoubiquitination of NOLC1 and TCOF1: monoubiquitination promotes the formation of a NOLC1-TCOF1 complex that acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification.,TA-KRP,TAKRP,KBTBD8,Cell Biology & Developmental Biology,KBTBD8
- Gene ID
- 84541
- UniProt
- Q8NFY9
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