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Insulin Receptor antibody (AA 1281-1382)

Name: Insulin Receptor antibody (AA 1281-1382)
Brand: antibodies-online
SKU: ABIN7267890
Price: 877.74 USD
Availability: InStock

INSR Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated

Western blot analysis of extracts of various cell lines, using Insulin Receptor Rabbit pAb (ABIN7267890) at 1:3000 dilution. (Insulin Receptor antibody (AA 1281-1382))

Immunoprecipitation analysis of 300 μg extracts of HeLa cells using 3 μg Insulin Receptor antibody (ABIN7267890). (Insulin Receptor antibody (AA 1281-1382))

2 images

Catalog No. ABIN7267890

Datasheet as PDF

Target See all Insulin Receptor (INSR) Antibodies

Insulin Receptor (INSR)
Binding Specificity
16

14

13

11

8

8

8

5

5

5

4

4

4

4

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1281-1382
Reactivity
168

87

76

17

12

9

8

7

6

6

4

3

2

2

1

1

1

1

1

1

1

1
Human
Host
157

25

2

1
Rabbit
Compatible Secondaries
Clonality
146

39
Polyclonal
Conjugate
118

15

14

5

4

4

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
This Insulin Receptor antibody is un-conjugated
Application
133

77

53

31

18

15

15

15

13

13

9

5

4

4

3

2

2

2

1

1

1

1
Western Blotting (WB), Immunoprecipitation (IP)

Purpose

Insulin Receptor Rabbit pAb

Sequence

PTFLEIVNLL KDDLHPSFPE VSFFHSEENK APESEELEME FEDMENVPLD RSSHCQREEA GGRDGGSSLG FKRSYEEHIP YTHMNGGKKN GRILTLPRSN PS

Cross-Reactivity

Human, Mouse, Rat

Characteristics

Polyclonal Antibodies

Purification

Affinity purification

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1281-1382 of human INSR (NP_000199.2).

Isotype

IgG

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INSR Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

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INSR Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

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INSR Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Insulin Receptor (INSR) (AA 27-57), (N-Term) antibody
INSR Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB1421 unconjugated

anti-Insulin Receptor (INSR) (C-Term) antibody
INSR Reactivity: Human, Mouse, Rat, Dog, Monkey, Horse, Cow, Guinea Pig, Rabbit, Pig, Chicken, Sheep, Hamster, Avian, Cat, Donkey, Goat WB Host: Goat Polyclonal unconjugated

anti-Insulin Receptor (INSR) (C-Term) antibody
KO Validated INSR Reactivity: Human WB, ICC, IF, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Insulin Receptor (INSR) (AA 1325-1358) antibody
INSR Reactivity: Mouse WB Host: Rabbit Polyclonal RB50340 unconjugated

anti-Insulin Receptor (INSR) (AA 1023-1298) antibody
INSR Reactivity: Human IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated

anti-Insulin Receptor (INSR) (AA 51-150) antibody
INSR Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

Application Notes

WB,1:500 - 1:2000,IP,1:50 - 1:200

Restrictions

For Research Use only
Format

Liquid

Buffer

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Store at -20°C. Avoid freeze / thaw cycles.
Target

Insulin Receptor (INSR)

Alternative Name

INSR (INSR Products)

Background

This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.,CD220,HHF5,INSR,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,Insulin and insulin-like,Endocrine & Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Immunology & Inflammation,CD markers,Neuroscience,Cardiovascular,Heart,Cardiovascular diseases,Heart disease,INSR

Molecular Weight

155kDa/156kDa

Gene ID

3643

UniProt

P06213

Pathways

NF-kappaB Signaling, RTK Signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity