IgG3 antibody

Catalog No. ABIN7267839

Product Details anti-IgG3 Antibody

Target: IgG3

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IgG3 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Human IgG3 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Human IgG3

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IgG3

Target: IgG3

Alternative Name: IGHG3 (IgG3 Products)

Synonyms: IgG3 antibody, Immunoglobulin heavy constant gamma 3 antibody, immunoglobulin heavy constant gamma 3 (G3m marker) antibody, Ighg3 antibody, IGHG3 antibody

Target Type: Antibody

Background: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.,IgG3,Immunology & Inflammation,IGHG3

Molecular Weight: kDa

Gene ID: 3502

UniProt: P01860