Histone H2B antibody (meLys5)

Catalog No. ABIN7267735

Product Details anti-Histone H2B Antibody

Target: Histone H2B

Binding Specificity: meLys5

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H2B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: MonoMethyl-Histone H2B-K5 Rabbit pAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Methylated Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide of Human H2BK5me1.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Histone H2B

Target: Histone H2B

Abstract: Histone H2B Products

Synonyms: Hist1h2bc antibody, H2B antibody, HISTONE H2B antibody, MRN17.11 antibody, MRN17_11 antibody, histone B2 antibody, H2B1 antibody, HIS2B antibody, histone cluster 1 H2B family member k antibody, histone H2B antibody, histone B2 antibody, histone H2B.3 antibody, Hist1h2bk antibody, H2B antibody, HTB2 antibody, THAPSDRAFT_27352 antibody, THAPSDRAFT_37309 antibody, THAPS_6947 antibody, THAPSDRAFT_34210 antibody, LOC426037 antibody, LOC107802329 antibody

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. The protein has antibacterial and antifungal antimicrobial activity. [provided by RefSeq, Aug 2015],GL105,H2B,H2B.1,H2BFQ,H2BGL105,H2BQ,Histone H2B,HIST2H2BE,Epigenetics & Nuclear Signaling,Histones,Epigenetics & Nuclear Signaling,Epigenetic Modifications,Methylation,Histone H2B

Molecular Weight: 13kDa

Gene ID: 8349

UniProt: Q16778