HEXIM2 antibody (AA 147-286)

Catalog No. ABIN7267637

Product Details anti-HEXIM2 Antibody

Target: HEXIM2 (Hexamthylene Bis-Acetamide Inducible 2 (HEXIM2))

Binding Specificity: AA 147-286

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HEXIM2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: HEXIM2 Rabbit pAb

Sequence: LMNDRDPEEP NLDVPHGISH PGSSGESEAG DSDGRGRAHG EFQRKDFSET YERFHTESLQ GRSKQELVRD YLELEKRLSQ AEEETRRLQQ LQACTGQQSC RQVEELAAEV QRLRTENQRL RQENQMWNRE GCRCDEEPGT

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 147-286 of human HEXIM2 (NP_653209.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HEXIM2

Target: HEXIM2 (Hexamthylene Bis-Acetamide Inducible 2 (HEXIM2))

Alternative Name: HEXIM2 (HEXIM2 Products)

Synonyms: 4933402L21Rik antibody, hexamethylene bisacetamide inducible 2 antibody, hexamethylene bis-acetamide inducible 2 antibody, HEXIM2 antibody, Hexim2 antibody

Background: This gene encodes a member of the HEXIM family of proteins. This protein is a component of the 7SK small nuclear ribonucleoprotein. This protein has been found to negatively regulate the kinase activity of the cyclin-dependent kinase P-TEFb, which phosphorylates multiple target proteins to promote transcriptional elongation. This gene is located approximately 7 kb downstream from related family member HEXIM1 on chromosome 17. Alternative splicing results in multiple transcript variants.,HEXIM2,L3,Epigenetics & Nuclear Signaling,HEXIM2

Molecular Weight: 32kDa

Gene ID: 124790

UniProt: Q96MH2