HBG1 antibody (AA 1-100)

Catalog No. ABIN7267610

Product Details anti-HBG1 Antibody

Target: HBG1 (Hemoglobin, gamma A (HBG1))

Binding Specificity: AA 1-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HBG1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: HBG1 Rabbit pAb

Sequence: MGHFTEEDKA TITSLWGKVN VEDAGGETLG RLLVVYPWTQ RFFDSFGNLS SASAIMGNPK VKAHGKKVLT SLGDATKHLD DLKGTFAQLS ELHCDKLHVD

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HBG1 (NP_000550.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HBG1

Target: HBG1 (Hemoglobin, gamma A (HBG1))

Alternative Name: HBG1 (HBG1 Products)

Synonyms: Hbe1 antibody, Hbb-y antibody, HBGA antibody, HBGR antibody, HSGGL1 antibody, beta-globin antibody, hbb1 antibody, hbga antibody, hbgr antibody, hsggl1 antibody, HBG2 antibody, HBG1 antibody, hemoglobin subunit gamma 1 antibody, hemoglobin subunit gamma 1 L homeolog antibody, hemoglobin, gamma G antibody, hemoglobin subunit gamma-1 antibody, Hbg1 antibody, HBG1 antibody, hbg1.L antibody, LOC100982657 antibody

Background: The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.,HBG1,HBG-T2,HBGA,HBGR,HSGGL1,PRO2979,HBG1

Molecular Weight: 16kDa

Gene ID: 3047

UniProt: P69891