HEY2 antibody (AA 1-100)

Catalog No. ABIN7267562

Product Details anti-HEY2 Antibody

Target: HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))

Binding Specificity: AA 1-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HEY2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: HEY2 Rabbit pAb

Sequence: MKRPCEETTS ESDMDETIDV GSENNYSGQS TSSVIRLNSP TTTSQIMARK KRRGIIEKRR RDRINNSLSE LRRLVPTAFE KQGSAKLEKA EILQMTVDHL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HEY2 (NP_036391.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HEY2

Target: HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))

Alternative Name: HEY2 (HEY2 Products)

Synonyms: CHF1 antibody, GRIDLOCK antibody, GRL antibody, HERP1 antibody, HESR2 antibody, HRT2 antibody, bHLHb32 antibody, Herp1 antibody, Hrt2 antibody, hesr2 antibody, grl antibody, zgc:136746 antibody, hes related family bHLH transcription factor with YRPW motif 2 antibody, hairy/enhancer-of-split related with YRPW motif 2 antibody, hes-related family bHLH transcription factor with YRPW motif 2 antibody, HEY2 antibody, Hey2 antibody, hey2 antibody

Background: This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.,HEY2,CHF1,GRIDLOCK,GRL,HERP1,HESR2,HRT2,bHLHb32,Epigenetics & Nuclear Signaling,Transcription Factors,Stem Cells,Cardiovascular,Heart,Cardiogenesis,HEY2

Molecular Weight: 35kDa

Gene ID: 23493

UniProt: Q9UBP5

Pathways: Regulation of Muscle Cell Differentiation