CD235b/GYPB antibody (AA 1-91)

Catalog No. ABIN7267475

Product Details anti-CD235b/GYPB Antibody

Target: CD235b/GYPB (GYPB) (Glycophorin B (GYPB))

Binding Specificity: AA 1-91

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD235b/GYPB antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: GYPB Rabbit pAb

Sequence: MYGKIIFVLL LSEIVSISAL STTEVAMHTS TSSSVTKSYI SSQTNGETGQ LVHRFTVPAP VVIILIILCV MAGIIGTILL ISYTIRRLIK A

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-91 of human GYPB (NP_002091.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CD235b/GYPB

Target: CD235b/GYPB (GYPB) (Glycophorin B (GYPB))

Alternative Name: GYPB (GYPB Products)

Synonyms: CD235b antibody, GPB antibody, GPB.NY antibody, GYPHe.NY antibody, GpMiIII antibody, HGpMiIII antibody, HGpMiVI antibody, HGpMiX antibody, MNS antibody, PAS-3 antibody, SS antibody, glycophorin B (MNS blood group) antibody, GYPB antibody

Background: Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97 % sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. Alternate splicing results in multiple transcript variants.,GYPB,CD235b,GPB,GYP,MNS,PAS-3,SS,Immunology & Inflammation,CD markers,Cardiovascular,Blood,Blood Cell Antigens,GYPB

Molecular Weight: 6kDa/9kDa

Gene ID: 2994

UniProt: P06028