GSTA3 antibody (AA 1-222)

Catalog No. ABIN7267440

Product Details anti-GSTA3 Antibody

Target: GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))

Binding Specificity: AA 1-222

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSTA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: GSTA3 Rabbit pAb

Sequence: MAGKPKLHYF NGRGRMEPIR WLLAAAGVEF EEKFIGSAED LGKLRNDGSL MFQQVPMVEI DGMKLVQTRA ILNYIASKYN LYGKDIKERA LIDMYTEGMA DLNEMILLLP LCRPEEKDAK IALIKEKTKS RYFPAFEKVL QSHGQDYLVG NKLSRADISL VELLYYVEEL DSSLISNFPL LKALKTRISN LPTVKKFLQP GSPRKPPADA KALEEARKIF RF

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-222 of human GSTA3 (NP_000838.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GSTA3

Target: GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))

Alternative Name: GSTA3 (GSTA3 Products)

Synonyms: GSTA3 antibody, GST antibody, GSTA1 antibody, GSTA3-3 antibody, GTA3 antibody, GSTA2 antibody, Gst2-3 antibody, Yc2 antibody, glutathione S-transferase alpha 3 antibody, glutathione S-transferase A2 antibody, glutathione S-transferase antibody, glutathione S-transferase, alpha 3 antibody, glutathione S-transferase Yc antibody, GSTA3 antibody, LOC474938 antibody, gsta3 antibody, Gsta3 antibody, LOC100328911 antibody

Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008],GSTA3,GSTA3-3,GTA3,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Drug metabolism,GSTA3

Molecular Weight: 25kDa

Gene ID: 2940

UniProt: Q16772