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GIT2 antibody (AA 450-510)

GIT2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7267315
  • Target See all GIT2 Antibodies
    GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))
    Binding Specificity
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 450-510
    Reactivity
    • 45
    • 14
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 39
    • 7
    Rabbit
    Clonality
    • 41
    • 5
    Polyclonal
    Conjugate
    • 28
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This GIT2 antibody is un-conjugated
    Application
    • 24
    • 12
    • 7
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purpose
    GIT2 Rabbit pAb
    Sequence
    ASRLEKQNST PESDYDNTPN DMEPDGMGSS RKGRQRSMVW PGDGLVPDTA EPHVAPSPTL P
    Cross-Reactivity
    Human
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 450-510 of human GIT2 (NP_476511.1).
    Isotype
    IgG
    Top Product
    Discover our top product GIT2 Primary Antibody
  • Application Notes
    WB,1:200 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))
    Alternative Name
    GIT2 (GIT2 Products)
    Synonyms
    CAT-2 antibody, CAT2 antibody, cat-2 antibody, xgit2 antibody, git2 antibody, si:dkey-234h16.4 antibody, 1500036H07Rik antibody, 5830420E16Rik antibody, 6430510B20Rik antibody, 9630056M03Rik antibody, B230104M05Rik antibody, mKIAA0148 antibody, zgc:158416 antibody, GIT ArfGAP 2 antibody, G protein-coupled receptor kinase interacting ArfGAP 2 antibody, G protein-coupled receptor kinase interacting ArfGAP 2a antibody, G protein-coupled receptor kinase-interactor 2 antibody, G protein-coupled receptor kinase interacting ArfGAP 2 L homeolog antibody, G protein-coupled receptor kinase interacting ArfGAP 2b antibody, GIT2 antibody, git2 antibody, git2a antibody, Git2 antibody, git2.L antibody, git2b antibody
    Background
    This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding.,GIT2,CAT-2,CAT2,PKL,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Kinase,Cell Biology & Developmental Biology,Cytoskeleton,Actins,GIT2
    Molecular Weight
    52kDa, 70-84kDa
    Gene ID
    9815
    UniProt
    Q14161
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
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