GPR4 antibody (AA 283-362)

Catalog No. ABIN7267307

Product Details anti-GPR4 Antibody

Target: GPR4 (G Protein-Coupled Receptor 4 (GPR4))

Binding Specificity: AA 283-362

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR4 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: GPR4 Rabbit pAb

Sequence: PILYCLVNEG ARSDVAKALH NLLRFLASDK PQEMANASLT LETPLTSKRN STAKAMTGSW AATPPSQGDQ VQLKMLPPAQ

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 283-362 of human GPR4 (NP_005273.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GPR4

Target: GPR4 (G Protein-Coupled Receptor 4 (GPR4))

Alternative Name: GPR4 (GPR4 Products)

Background: Proton-sensing G-protein coupled receptor couples to multiple intracellular signaling pathways, including GNAS/cAMP, GNAQ/phospholipase C (PLC, and GNA12/GNA13/Rho pathways. Acidosis-induced GPR4 activation increases paracellular gap formation and permeability of vascular endothelial cells through the GNA12/GNA13/Rho GTPase signaling pathway. In the brain may mediate central respiratory sensitivity to CO(2H(+ (By similarity.,GPR4,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),GPR4

Molecular Weight: 40kDa

Gene ID: 2828

UniProt: P46093