FUT3 antibody (AA 1-100)

Catalog No. ABIN7267273

Product Details anti-FUT3 Antibody

Target: FUT3 (Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3))

Binding Specificity: AA 1-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUT3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: FUT3 Rabbit pAb

Sequence: MDPLGAAKPQ WPWRRCLAAL LFQLLVAVCF FSYLRVSRDD ATGSPRAPSG SSRQDTTPTR PTLLILLWTW PFHIPVALSR CSEMVPGTAD CHITADRKVY

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FUT3 (NP_000140.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FUT3

Target: FUT3 (Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3))

Alternative Name: FUT3 (FUT3 Products)

Synonyms: CD174 antibody, FT3B antibody, FucT-III antibody, LE antibody, Les antibody, fut356 antibody, FUT3 antibody, ATFUT3 antibody, F1M20.10 antibody, F1M20_10 antibody, fucosyltransferase 3 antibody, fucosyltransferase 3 (Lewis blood group) antibody, fucosyltransferase 3 (Lewis blood group) L homeolog antibody, fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) antibody, fucosyltransferase 3 antibody, galactoside 3(4)-L-fucosyltransferase antibody, FUT3 antibody, fut3.L antibody, fut3 antibody, LOC697452 antibody, LOC697582 antibody

Background: The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.,FUT3,CD174,FT3B,FucT-III,LE,Les,Immunology & Inflammation,CD markers,Cardiovascular,Blood,Blood Cell Antigens,FUT3

Molecular Weight: 42kDa

Gene ID: 2525

UniProt: P21217