FREM2 antibody (AA 47-300)

Catalog No. ABIN7267260

Product Details anti-FREM2 Antibody

Target: FREM2 (Fras1 Related Extracellular Matrix Protein 2 (FREM2))

Binding Specificity: AA 47-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FREM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: FREM2 Rabbit pAb

Sequence: QPAAFGRALL SPGLAGAAGV PAEEAIVLAN RGLRVPFGRE VWLDPLHDLV LQVQPGDRCA VSVLDNDALA QRPGRLSPKR FPCDFGPGEV RYSHLGARSP SRDRVRLQLR YDAPGGAVVL PLVLEVEVVF TQLEVVTRNL PLVVEELLGT SNALDARSLE FAFQPETEEC RVGILSGLGA LPRYGELLHY PQVPGGAREG GAPETLLMDC KAFQELGVRY RHTAASRSPN RDWIPMVVEL RSRGAPVGSP ALKR

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 47-300 of human FREM2 (NP_997244.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FREM2

Target: FREM2 (Fras1 Related Extracellular Matrix Protein 2 (FREM2))

Alternative Name: FREM2 (FREM2 Products)

Background: This gene encodes an integral membrane protein containing numerous CSPG (chondroitin sulfate proteoglycan element) repeats and Calx-beta domains. The encoded protein localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions. This protein is important for the integrity of skin and renal epithelia. Mutations in this gene are associated with Fraser syndrome.,FREM2,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cell Adhesion Molecules,Cytoskeleton,Neuroscience,Calcium Signaling,FREM2

Molecular Weight: 295kDa/351kDa

Gene ID: 341640

UniProt: Q5SZK8