FKBP1B antibody (AA 1-80)

Catalog No. ABIN7267212

Product Details anti-FKBP1B Antibody

Target: FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))

Binding Specificity: AA 1-80

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP1B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purpose: FKBP1B Rabbit pAb

Sequence: MGVEIETISP GDGRTFPKKG QTCVVHYTGM LQNGKKFDSS RDRNKPFKFR IGKQEVIKGF EEGAAQLGPL SPLPICPHPC

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-80 of human FKBP1B (NP_473374.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FKBP1B

Target: FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))

Alternative Name: FKBP1B (FKBP1B Products)

Background: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms.,FKBP1B,FKBP12.6,FKBP1L,OTK4,PKBP1L,PPIase,Immunology & Inflammation,Neuroscience,Calcium Signaling,FKBP1B

Molecular Weight: 8kDa/11kDa

Gene ID: 2281

UniProt: P68106

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Negative Regulation of Transporter Activity