FCN3 antibody (AA 13-288)

Catalog No. ABIN7267202

Product Details anti-FCN3 Antibody

Target: FCN3 (Ficolin (Collagen/fibrinogen Domain Containing) 3 (Hakata Antigen) (FCN3))

Binding Specificity: AA 13-288

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FCN3 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: FCN3 Rabbit pAb

Sequence: LLLGGPACLK TQEHPSCPGP RELEASKVVL LPSCPGAPGS PGEKGAPGPQ GPPGPPGKMG PKGEPGPRNC RELLSQGATL SGWYHLCLPE GRALPVFCDM DTEGGGWLVF QRRQDGSVDF FRSWSSYRAG FGNQESEFWL GNENLHQLTL QGNWELRVEL EDFNGNRTFA HYATFRLLGE VDHYQLALGK FSEGTAGDSL SLHSGRPFTT YDADHDSSNS NCAVIVHGAW WYASCYRSNL NGRYAVSEAA AHKYGIDWAS GRGVGHPYRR VRMMLR

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 13-288 of human FCN3 (NP_775628.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FCN3

Target: FCN3 (Ficolin (Collagen/fibrinogen Domain Containing) 3 (Hakata Antigen) (FCN3))

Alternative Name: FCN3 (FCN3 Products)

Synonyms: FCNH antibody, HAKA1 antibody, ficolin 3 antibody, ficolin-3 antibody, FCN3 antibody, Fcn3 antibody, fcn3-A antibody

Background: Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum, there are two types of ficolins, both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein, which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus, has been shown to have a calcium-independent lectin activity. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants, each encoding a distinct isoform, have been identified.,FCN3,FCNH,HAKA1,ficolin-3,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Immunology & Inflammation,FCN3

Molecular Weight: 31kDa/32kDa

Gene ID: 8547

UniProt: O75636

Pathways: Complement System