FADD antibody
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- Target See all FADD Antibodies
- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This FADD antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Purpose
- FADD Rabbit mAb
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Monoclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- A synthesized peptide derived from human FADD
- Isotype
- IgG
- Top Product
- Discover our top product FADD Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
- Alternative Name
- FADD (FADD Products)
- Synonyms
- MORT1 antibody, Mort1/FADD antibody, Mort1 antibody, TNFRSF6 antibody, adaptor antibody, fadd antibody, mort1 antibody, xfadd antibody, Fas associated via death domain antibody, Fas (TNFRSF6)-associated via death domain antibody, Fas associated via death domain S homeolog antibody, Fas (tnfrsf6)-associated via death domain antibody, FADD antibody, Fadd antibody, fadd.S antibody, fadd antibody
- Background
- Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95 or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.,Mort1/FADD,FADD
- Molecular Weight
- 28kDa
- Gene ID
- 14082
- UniProt
- Q61160
- Pathways
- Apoptosis, TLR Signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
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