FAM105B antibody

Catalog No. ABIN7267099

Product Details anti-FAM105B Antibody

Target: FAM105B (Family with Sequence Similarity 105, Member B (FAM105B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM105B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: OTULIN Rabbit pAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant protein of human OTULIN.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FAM105B

Target: FAM105B (Family with Sequence Similarity 105, Member B (FAM105B))

Alternative Name: OTULIN (FAM105B Products)

Synonyms: C79097 antibody, OTU deubiquitinase with linear linkage specificity antibody, OTULIN antibody, Otulin antibody

Background: This gene encodes a member of the peptidase C65 family of ubiquitin isopeptidases. Members of this family remove ubiquitin from proteins. The encoded enzyme specifically recognizes and removes M1(Met1)-linked, or linear, ubiquitin chains from protein substrates. Linear ubiquitin chains are known to regulate the NF-kappa B signaling pathway in the context of immunity and inflammation. Mutations in this gene cause a potentially fatal autoinflammatory syndrome in human patients.,GUM, AIPDS, FAM105B,OTULIN

Molecular Weight: 40kDa

Gene ID: 90268

UniProt: Q96BN8