FBXO32 antibody

Catalog No. ABIN7267090

Product Details anti-FBXO32 Antibody

Target: FBXO32 (F-Box Protein 32 (FBXO32))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FBXO32 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: Fbx32/FBOX32 Rabbit mAb

Cross-Reactivity: Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Fbx32/FBOX32

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000, IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FBXO32

Target: FBXO32 (F-Box Protein 32 (FBXO32))

Alternative Name: FBXO32 (FBXO32 Products)

Synonyms: MGC56479 antibody, zgc:56479 antibody, Fbx32 antibody, MAFbx antibody, 4833442G10Rik antibody, AI430017 antibody, ATROGIN1 antibody, Gm20361 antibody, Atrogin1 antibody, F-box protein 32 antibody, fbxo32 antibody, FBXO32 antibody, Fbxo32 antibody

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011],Fbx32, MAFbx,Cardiovascular,Cell Biology & Developmental Biology,Heart,Heart_Hypertrophy,Mesenchymal Stem Cells,Stem Cells,Ubiquitin,FBXO32

Molecular Weight: 42kDa

Gene ID: 114907

UniProt: Q969P5