EYA3 antibody (AA 1-300)

Catalog No. ABIN7267073

Product Details anti-EYA3 Antibody

Target: EYA3 (Eyes Absent Homolog 3 (EYA3))

Binding Specificity: AA 1-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EYA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: EYA3 Rabbit pAb

Sequence: MEEEQDLPEQ PVKKAKMQES GEQTISQVSN PDVSDQKPET SSLASNLPMS EEIMTCTDYI PRSSNDYTSQ MYSAKPYAHI LSVPVSETAY PGQTQYQTLQ QTQPYAVYPQ ATQTYGLPPF GALWPGMKPE SGLIQTPSPS QHSVLTCTTG LTTSQPSPAH YSYPIQASST NASLISTSST IANIPAAAVA SISNQDYPTY TILGQNQYQA CYPSSSFGVT GQTNSDAEST TLAATTYQSE KPSVMAPAPA AQRLSSGDPS TSPSLSQTTP SKDTDDQSRK NMTSKNRGKR KADATSSQDS

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human EYA3 (NP_001981.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EYA3

Target: EYA3 (Eyes Absent Homolog 3 (EYA3))

Alternative Name: EYA3 (EYA3 Products)

Background: This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants.,EYA3,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Dephosphorylation,Signal Transduction,Stem Cells,Neural Stem Cells,EYA3

Molecular Weight: 48kDa/56kDa/57kDa/58kDa/62kDa

Gene ID: 2140

UniProt: Q99504

Pathways: Positive Regulation of Response to DNA Damage Stimulus