EIF4E antibody
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- Target See all EIF4E Antibodies
- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This EIF4E antibody is un-conjugated
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Purpose
- eIF4E Rabbit mAb
- Cross-Reactivity
- Mouse, Rat
- Characteristics
- Monoclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- A synthesized peptide derived from human eIF4E
- Isotype
- IgG
- Top Product
- Discover our top product EIF4E Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000,IP,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
- Alternative Name
- EIF4E (EIF4E Products)
- Background
- The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],AUTS19;CBP;EIF4E1;EIF4EL1;EIF4F;eIF-4E;EIF4E,Angiogenesis,Cardiovascular,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,Immunology & Inflammation,Insulin Receptor Signaling Pathway,Protein phosphorylation,Signal Transduction,Translation Control,Translational Control_Regulation of eIF4 and p70 S6 Kinase,EIF4E
- Molecular Weight
- 30kDa
- Gene ID
- 1977
- UniProt
- P06730
- Pathways
- BCR Signaling
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