EDEM2 antibody (AA 399-578)

Catalog No. ABIN7267004

Product Details anti-EDEM2 Antibody

Target: EDEM2 (ER Degradation Enhancer, Mannosidase alpha-Like 2 (EDEM2))

Binding Specificity: AA 399-578

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EDEM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: EDEM2 Rabbit pAb

Sequence: SIEKISKVEC GFATIKDLRD HKLDNRMESF FLAETVKYLY LLFDPTNFIH NNGSTFDAVI TPYGECILGA GGYIFNTEAH PIDPAALHCC QRLKEEQWEV EDLMREFYSL KRSRSKFQKN TVSSGPWEPP ARPGTLFSPE NHDQARERKP AKQKVPLLSC PSQPFTSKLA LLGQVFLDSS

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 399-578 of human EDEM2 (NP_060687.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EDEM2

Target: EDEM2 (ER Degradation Enhancer, Mannosidase alpha-Like 2 (EDEM2))

Alternative Name: EDEM2 (EDEM2 Products)

Background: In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 [PubMed 15537790]).,EDEM2,C20orf31,C20orf49,bA4204.1,Signal Transduction,EDEM2

Gene ID: 55741

UniProt: Q9BV94