ERVW-1 antibody (AA 1-100)

Catalog No. ABIN7266937

Product Details anti-ERVW-1 Antibody

Target: ERVW-1 (Endogenous Retrovirus Group W, Member 1 (ERVW-1))

Binding Specificity: AA 1-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERVW-1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: ERVW-1 Rabbit pAb

Sequence: MALPYHIFLF TVLLPSFTLT APPPCRCMTS SSPYQEFLWR MQRPGNIDAP SYRSLSKGTP TFTAHTHMPR NCYHSATLCM HANTHYWTGK MINPSCPGGL

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ERVW-1 (NP_001124397.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ERVW-1

Target: ERVW-1 (Endogenous Retrovirus Group W, Member 1 (ERVW-1))

Alternative Name: ERVW-1 (ERVW-1 Products)

Synonyms: ENV antibody, ENVW antibody, ERVWE1 antibody, HERV-7q antibody, HERV-W-ENV antibody, HERV7Q antibody, HERVW antibody, HERVWENV antibody, endogenous retrovirus group W member 1, envelope antibody, ERVW-1 antibody

Background: Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Alternatively spliced transcript variants encoding the same protein have been found for this gene.,ERVW-1;ENV;ENVW;ERVWE1;HERV-7q;HERV-W-ENV;HERV7Q;HERVW;HERVWENV,Cell Biology & Developmental Biology,ERVW-1

Molecular Weight: 59kDa

Gene ID: 30816

UniProt: Q9UQF0