EML4 antibody (AA 360-560)

Catalog No. ABIN7266891

Product Details anti-EML4 Antibody

Target: EML4 (Echinoderm Microtubule Associated Protein Like 4 (EML4))

Binding Specificity: AA 360-560

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EML4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purpose: EML4 Rabbit pAb

Sequence: GTFERGVGCL DFSKADSGVH LCVIDDSNEH MLTVWDWQKK AKGAEIKTTN EVVLAVEFHP TDANTIITCG KSHIFFWTWS GNSLTRKQGI FGKYEKPKFV QCLAFLGNGD VLTGDSGGVM LIWSKTTVEP TPGKGPKGVY QISKQIKAHD GSVFTLCQMR NGMLLTGGGK DRKIILWDHD LNPEREIEVP DQYGTIRAVA E

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 360-560 of human EML4 (NP_061936.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EML4

Target: EML4 (Echinoderm Microtubule Associated Protein Like 4 (EML4))

Alternative Name: EML4 (EML4 Products)

Background: This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants.,EML4,C2orf2,ELP120,EMAP-4,EMAPL4,ROPP120,Cell Biology & Developmental Biology,Cytoskeleton,Microtubules,EML4

Molecular Weight: 102kDa/108kDa

Gene ID: 27436

UniProt: Q9HC35