Dystrophin antibody
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- Target See all Dystrophin (DMD) Antibodies
- Dystrophin (DMD)
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This Dystrophin antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purpose
- Dystrophin Rabbit mAb
- Cross-Reactivity
- Mouse, Rat
- Characteristics
- Monoclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- A synthesized peptide derived from human Dystrophin
- Isotype
- IgG
- Top Product
- Discover our top product DMD Primary Antibody
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- Application Notes
- IHC,1:50 - 1:200,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Dystrophin (DMD)
- Alternative Name
- DMD (DMD Products)
- Background
- This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016],BMD, CMD3B, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Microfilaments,Mesenchymal Stem Cells,Neurodegenerative Diseases,Neuroscience,Signal Transduction,Stem Cells,DMD
- Molecular Weight
- 427kDa
- Gene ID
- 1756
- UniProt
- P11532
- Pathways
- Skeletal Muscle Fiber Development
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