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Dystrophin antibody

DMD Reactivity: Human IHC, IF Host: Rabbit Monoclonal unconjugated
Catalog No. ABIN7266871
  • Target See all Dystrophin (DMD) Antibodies
    Dystrophin (DMD)
    Reactivity
    • 48
    • 18
    • 17
    • 5
    Human
    Host
    • 32
    • 17
    Rabbit
    Clonality
    • 26
    • 23
    Monoclonal
    Conjugate
    • 29
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This Dystrophin antibody is un-conjugated
    Application
    • 22
    • 19
    • 15
    • 10
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Purpose
    Dystrophin Rabbit mAb
    Cross-Reactivity
    Mouse, Rat
    Characteristics
    Monoclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    A synthesized peptide derived from human Dystrophin
    Isotype
    IgG
    Top Product
    Discover our top product DMD Primary Antibody
  • Application Notes
    IHC,1:50 - 1:200,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Dystrophin (DMD)
    Alternative Name
    DMD (DMD Products)
    Background
    This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016],BMD, CMD3B, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Microfilaments,Mesenchymal Stem Cells,Neurodegenerative Diseases,Neuroscience,Signal Transduction,Stem Cells,DMD
    Molecular Weight
    427kDa
    Gene ID
    1756
    UniProt
    P11532
    Pathways
    Skeletal Muscle Fiber Development
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