DUSP2 antibody (AA 150-250)

Catalog No. ABIN7266847

Product Details anti-DUSP2 Antibody

Target: DUSP2 (Dual Specificity Phosphatase 2 (DUSP2))

Binding Specificity: AA 150-250

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: DUSP2 Rabbit pAb

Sequence: ALPPTGDKTS RSDSRAPVYD QGGPVEILPY LFLGSCSHSS DLQGLQACGI TAVLNVSASC PNHFEGLFRY KSIPVEDNQM VEISAWFQEA IGFIDWVKNS G

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human DUSP2 (NP_004409.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DUSP2

Target: DUSP2 (Dual Specificity Phosphatase 2 (DUSP2))

Alternative Name: DUSP2 (DUSP2 Products)

Synonyms: zgc:91929 antibody, wu:fj40g04 antibody, PAC-1 antibody, PAC1 antibody, dual specificity phosphatase 2 antibody, dusp2 antibody, DUSP2 antibody, Dusp2 antibody

Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus.,DUSP2,PAC-1,PAC1,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,p53 pathway,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Endocrine & Metabolism,DUSP2

Molecular Weight: 34kDa

Gene ID: 1844

UniProt: Q05923