Desmoglein 3 antibody

Catalog No. ABIN7266741

Product Details anti-Desmoglein 3 Antibody

Target: Desmoglein 3 (DSG3)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Desmoglein 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: Desmoglein 3 Rabbit mAb

Cross-Reactivity: Human, Mouse

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Desmoglein 3

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Desmoglein 3

Target: Desmoglein 3 (DSG3)

Alternative Name: DSG3 (DSG3 Products)

Background: This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris. [provided by RefSeq, Jan 2016],CDHF6, PVA,Cell Adhesion,Cell Adhesion_Cadherins,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Signal Transduction,DSG3

Molecular Weight: 145kDa

Gene ID: 1830

UniProt: P32926