DCAF6 antibody (AA 460-650)

Catalog No. ABIN7266684

Product Details anti-DCAF6 Antibody

Target: DCAF6 (DDB1 and CUL4 Associated Factor 6 (DCAF6))

Binding Specificity: AA 460-650

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCAF6 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: IQWD1 Rabbit pAb

Sequence: DNNNEKLSPK PGTGEPVLSL HYSTEGTTTS TIKLNFTDEW SSIASSSRGI GSHCKSEGQE ESFVPQSSVQ PPEGDSETKA PEESSEDVTK YQEGVSAENP VENHINITQS DKFTAKPLDS NSGERNDLNL DRSCGVPEES ASSEKAKEPE TSDQTSTESA TNENNTNPEP QFQTEATGPS AHEETSTRDS A

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 460-650 of human IQWD1 (NP_001017977.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DCAF6

Target: DCAF6 (DDB1 and CUL4 Associated Factor 6 (DCAF6))

Alternative Name: IQWD1 (DCAF6 Products)

Background: The protein encoded by this gene is a ligand-dependent coactivator of nuclear receptors, including nuclear receptor subfamily 3 group C member 1 (NR3C1), glucocorticoid receptor (GR), and androgen receptor (AR). The encoded protein and DNA damage binding protein 2 (DDB2) may act as tumor promoters and tumor suppressors, respectively, by regulating the level of androgen receptor in prostate tissues. In addition, this protein can act with glucocorticoid receptor to promote human papillomavirus gene expression.,DCAF6,1200006M05Rik,ARCAP,IQWD1,MSTP055,NRIP,PC326,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Nuclear hormone receptors,Cancer,Signal Transduction,IQWD1

Molecular Weight: 96kDa/98kDa/103kDa/106kDa

Gene ID: 55827

UniProt: Q58WW2