Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

DMP1 antibody (AA 561-760)

DMTF1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7266560
  • Target See all DMP1 (DMTF1) Antibodies
    DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))
    Binding Specificity
    • 15
    • 15
    • 10
    • 10
    • 8
    • 8
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 561-760
    Reactivity
    • 90
    • 19
    • 19
    • 8
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    Human
    Host
    • 79
    • 8
    • 3
    • 1
    Rabbit
    Clonality
    • 84
    • 7
    Polyclonal
    Conjugate
    • 35
    • 8
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DMP1 antibody is un-conjugated
    Application
    • 65
    • 43
    • 26
    • 26
    • 8
    • 6
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Purpose
    DMTF1 Rabbit pAb
    Sequence
    VTVQCHTPRV IIQTVATEDI TSSISQAELT VDSDIQSSDF PEPPDALEAD TFPDEIHHPK MTVEPSFNDA HVSKFSDQNS TELMNSVMVR TEEEISDTDL KQEESPSDLA SAYVTEGLES PTIEEQVDQT IDDETILIVP SPHGFIQASD VIDTESVLPL TTLTDPILQH HQEESNIIGS SLGSPVSEDS KDVEDLVNCH
    Cross-Reactivity
    Human
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 561-760 of human DMTF1 (NP_066968.3).
    Isotype
    IgG
    Top Product
    Discover our top product DMTF1 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))
    Alternative Name
    DMTF1 (DMTF1 Products)
    Synonyms
    DMP1 antibody, DMTF antibody, hDMP1 antibody, Dimp antibody, Dmp1 antibody, DMTF1 antibody, zgc:92448 antibody, cyclin D binding myb like transcription factor 1 antibody, cyclin D binding myb-like transcription factor 1 antibody, DMTF1 antibody, Dmtf1 antibody, dmtf1 antibody
    Background
    This gene encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 40 % of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer. Multiple transcript variants encoding different isoforms have been found for this gene.,DMTF1,DMP1,DMTF,MRUL,hDMP1,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,Cyclins,DMTF1
    Gene ID
    9988
    UniProt
    Q9Y222
You are here:
Support