CRYGB antibody (AA 80-135)

Catalog No. ABIN7266531

Product Details anti-CRYGB Antibody

Target: CRYGB (Crystallin, gamma B (CRYGB))

Binding Specificity: AA 80-135

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRYGB antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: CRYGB Rabbit pAb

Sequence: CLIPPHSGAY RMKIYDRDEL RGQMSELTDD CISVQDRFHL TEIHSLNVLE GSWILY

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 80-135 of human CRYGB (NP_005201.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CRYGB

Target: CRYGB (Crystallin, gamma B (CRYGB))

Alternative Name: CRYGB (CRYGB Products)

Synonyms: MGC64303 antibody, cryg2 antibody, MGC85383 antibody, MGC146522 antibody, CRYG2 antibody, CTRCT39 antibody, Cryg-3 antibody, DGcry-3 antibody, Nop antibody, Cryg2 antibody, Len antibody, crystallin, gamma B antibody, crystallin gamma B L homeolog antibody, crystallin gamma B antibody, crygb antibody, crygb.L antibody, CRYGB antibody, Crygb antibody

Background: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.,CRYGB,CRYG2,CTRCT39,CRYGB

Molecular Weight: 20kDa

Gene ID: 1419

UniProt: P07316