CRY2 antibody (AA 36-266)

Catalog No. ABIN7266526

Product Details anti-CRY2 Antibody

Target: CRY2 (Cryptochrome 2 (Photolyase-Like) (CRY2))

Binding Specificity: AA 36-266

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRY2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: CRY2 Rabbit pAb

Sequence: PAPGTDSASS VHWFRKGLRL HDNPALLAAV RGARCVRCVY ILDPWFAASS SVGINRWRFL LQSLEDLDTS LRKLNSRLFV VRGQPADVFP RLFKEWGVTR LTFEYDSEPF GKERDAAIMK MAKEAGVEVV TENSHTLYDL DRIIELNGQK PPLTYKRFQA IISRMELPKK PVGLVTSQQM ESCRAEIQEN HDETYGVPSL EELGFPTEGL GPAVWQGGET EALARLDKHL E

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 36-266 of human CRY2 (NP_066940.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CRY2

Target: CRY2 (Cryptochrome 2 (Photolyase-Like) (CRY2))

Alternative Name: CRY2 (CRY2 Products)

Background: This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014],CRY2,HCRY2,PHLL2,Neuroscience,Cardiovascular,Blood,Blood Pressure regulation,CRY2

Molecular Weight: 60kDa/66kDa

Gene ID: 1408

UniProt: Q49AN0

Pathways: Response to Water Deprivation, Protein targeting to Nucleus