Coronavirus Spike Glycoprotein antibody
CoV S
Reactivity: SARS Coronavirus-2 (SARS-CoV-2)
ELISA, WB, IF, IP
Host: Rabbit
Polyclonal
unconjugated
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- Target See all Coronavirus Spike Glycoprotein (CoV S) Antibodies
- Coronavirus Spike Glycoprotein (CoV S)
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Reactivity
- SARS Coronavirus-2 (SARS-CoV-2)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Coronavirus Spike Glycoprotein antibody is un-conjugated
- Application
- ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
- Purpose
- SARS-CoV-2 Spike Rabbit pAb
- Cross-Reactivity
- SARS Coronavirus-2 (SARS-CoV-2)
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- A synthetic peptide of SARS-CoV-2 Spike.
- Isotype
- IgG
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- Application Notes
- ELISA,1:40000-1:160000,WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Coronavirus Spike Glycoprotein (CoV S)
- Alternative Name
- Spike (CoV S Products)
- Synonyms
- E2 antibody, E2 glycoprotein precursor antibody, S antibody
- Target Type
- Viral Protein
- Background
- The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. The spike is essential for both host specificity and viral infectivity. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. It''s been reported that SARS-CoV-2 (COVID-19 coronavirus, 2019-nCoV) can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion, Defines the range of the hosts and specificity of the virus, Main component to bind with the neutralizing antibody, Key target for vaccine design, Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate.,Spike
- Gene ID
- 43740568
- UniProt
- P0DTC2
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