CBFA2T3 antibody (AA 305-390)

Catalog No. ABIN7266502

Product Details anti-CBFA2T3 Antibody

Target: CBFA2T3 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3))

Binding Specificity: AA 305-390

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBFA2T3 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: CBFA2T3 Rabbit pAb

Sequence: DRDPLHPEHL SKRPCTLNPA QRYSPSNGPP QPTPPPHYRL EDIAMAHHFR DAYRHPDPRE LRERHRPLVV PGSRQEEVID HKLTER

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 305-390 of human CBFA2T3 (NP_005178.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CBFA2T3

Target: CBFA2T3 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3))

Alternative Name: CBFA2T3 (CBFA2T3 Products)

Synonyms: A630044F12Rik antibody, AI465270 antibody, AW229127 antibody, Cbfa2t3h antibody, ETO-2 antibody, Eto2 antibody, MTGR2 antibody, MTG16a antibody, MTG16b antibody, ETO2 antibody, MTG16 antibody, ZMYND4 antibody, core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human) antibody, CBFA2/RUNX1 translocation partner 3 antibody, Cbfa2t3 antibody, CBFA2T3 antibody

Background: This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16,21)(q24,q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.,CBFA2T3,ETO2,MTG16,MTGR2,RUNX1T3,ZMYND4,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor suppressors,CBFA2T3

Molecular Weight: 7kDa/62kDa/63kDa/71kDa

Gene ID: 863

UniProt: O75081