This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011],BLR1, CD185, MDR15,Blood,Cancer,Cardiovascular,CDs,Cell Intrinsic Innate Immunity Signaling Pathway,G protein signaling,G protein signaling_G-Protein-Coupled Receptors(GPCR),Immunology & Inflammation,Innate Immunity_Chemokines,Signal Transduction,CXCR5