CD70 antibody

Catalog No. ABIN7266215

Product Details anti-CD70 Antibody

Target: CD70 (CD70 Molecule (CD70))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD70 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purpose: CD70 Rabbit mAb

Cross-Reactivity: Human

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant protein of human CD70.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,FC,1:100 - 1:800

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % thimerosal, pH 7.4.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C (regular) or -20°C (long term). Avoid freeze

Target Details for CD70

Target: CD70 (CD70 Molecule (CD70))

Alternative Name: CD70 (CD70 Products)

Background: CD70 is a member of the TNF family whose expression is upregulated on DCs upon maturation. Its only receptor, CD27, is expressed on T cells and NK cells. The CD70/CD27 pathway promotes effector CD8+ T cells responses (by sustaining survival of CTLs) and influences polarization of CD4+ T cells, as it represents an alternative IL-12-independent pathway of Th1 priming and suppresses effector Th17 function.,CD70

Gene ID: 970

UniProt: P32970

Pathways: Cancer Immune Checkpoints