PD-L1 antibody (Extracellular Domain)
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- Target See all PD-L1 Antibodies
- PD-L1 (CD274 (PD-L1))
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Binding Specificity
- Extracellular Domain
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This PD-L1 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC)
- Purpose
- PD-L1/CD274 Rabbit mAb
- Cross-Reactivity
- Human
- Characteristics
- Monoclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human PD-L1 extracellular domain.
- Isotype
- IgG
- Top Product
- Discover our top product PD-L1 Primary Antibody
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anti-CD274 (PD-L1) (C-Term) antibody
Verified PD-L1 Reactivity: Human WB, FACS, ELISA, IF Host: Goat Polyclonal unconjugated
anti-CD274 (PD-L1) (AA 19-238) antibodyPD-L1 Reactivity: Human WB, FACS, IHC, ELISA, IF Host: Mouse Monoclonal 9B5F4 unconjugated
anti-CD274 (PD-L1) (AA 24-153) antibodyPD-L1 Reactivity: Human FACS, IHC, ELISA Host: Mouse Monoclonal 6D9A2 unconjugated
anti-CD274 (PD-L1) (AA 39-191) antibodyPD-L1 Reactivity: Human, Mouse WB, FACS, IHC, ELISA, IF, Coat, StM Host: Mouse Monoclonal PDL1-2746 unconjugated
anti-CD274 (PD-L1) (AA 48-290) antibodyPD-L1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-CD274 (PD-L1) (AA 34-241) antibodyPD-L1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-CD274 (PD-L1) (AA 24-153) antibodyPD-L1 Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 7D2A10 unconjugated
anti-CD274 (PD-L1) (C-Term) antibodyKO Validated PD-L1 Reactivity: Human WB, FACS, ICC, IF, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-CD274 (PD-L1) (AA 19-238) antibodyPD-L1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-CD274 (PD-L1) (AA 201-290) antibodyPD-L1 Reactivity: Mouse, Rat WB, ELISA, IF (cc), IHC (p), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
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- Application Notes
- IHC,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % thimerosal,0.05 % BSA,50 % glycerol, pH 7.3.
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PD-L1 (CD274 (PD-L1))
- Alternative Name
- PD-L1 (PD-L1 Products)
- Background
- This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.,B7-H,B7H1,PDL1,PD-L1,PDCD1L1,PDCD1LG1,CD274,Immunology & Inflammation,CD markers,PD-L1
- Molecular Weight
- 20kDa/33kDa
- Gene ID
- 29126
- UniProt
- Q9NZQ7
- Pathways
- Cancer Immune Checkpoints
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