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CRADD antibody

CRADD Reactivity: Human WB, IHC Host: Rabbit Monoclonal unconjugated
Catalog No. ABIN7266107
  • Target See all CRADD Antibodies
    CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))
    Reactivity
    • 43
    • 4
    • 2
    Human
    Host
    • 37
    • 6
    • 1
    • 1
    Rabbit
    Clonality
    • 38
    • 7
    Monoclonal
    Conjugate
    • 25
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CRADD antibody is un-conjugated
    Application
    • 34
    • 22
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Purpose
    RAIDD/CRADD Rabbit mAb
    Cross-Reactivity
    Human, Rat
    Characteristics
    Monoclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    A synthesized peptide derived from human RAIDD/CRADD
    Isotype
    IgG
    Top Product
    Discover our top product CRADD Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))
    Alternative Name
    CRADD (CRADD Products)
    Synonyms
    cradd antibody, MGC89035 antibody, zgc:101717 antibody, CRADD antibody, DKFZp468A2219 antibody, LOC100226369 antibody, raidd antibody, MGC78788 antibody, MRT34 antibody, RAIDD antibody, CASP2 and RIPK1 domain containing adaptor with death domain antibody, CASP2 and RIPK1 domain containing adaptor with death, gene 1 antibody, CASP2 and RIPK1 domain containing adaptor with death, gene 2 S homeolog antibody, CRADD antibody, cradd.1 antibody, cradd antibody, cradd.2.S antibody, Cradd antibody
    Background
    This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with mental retardation. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],MRT34, RAIDD,Apoptosis,Apoptosis_Mitochondrial Control of Apoptosis,Cancer,Cell Biology & Developmental Biology,Death Receptor Signaling Pathway,Invasion and Metastasis,CRADD
    Molecular Weight
    23kDa
    Gene ID
    8738
    UniProt
    P78560
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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