PLXDC2 antibody (AA 101-200)

Catalog No. ABIN717101

Product Details anti-PLXDC2 Antibody

Target: PLXDC2 (Plexin Domain Containing 2 (PLXDC2))

Binding Specificity: AA 101-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLXDC2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TEM7R

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PLXDC2

Target: PLXDC2 (Plexin Domain Containing 2 (PLXDC2))

Alternative Name: Tem7r (PLXDC2 Products)

Synonyms: MGC79122 antibody, TEM7R antibody, 1200007L24Rik antibody, 5430431D22Rik antibody, AI646728 antibody, AU022916 antibody, AV231634 antibody, Tem7r antibody, plexin domain containing 2 antibody, plexin domain containing 2 L homeolog antibody, PLXDC2 antibody, plxdc2.L antibody, plxdc2 antibody, Plxdc2 antibody

Background:

Synonyms: Tumor endothelial marker 7 related protein, Plexin domain containing 2, Plexin domain containing protein 2, Plexin domain-containing protein 2, PLXDC 2, plxdc2, PXDC2_HUMAN, TEM7R, Tumor endothelial marker 7-related protein.

Background: TEM7R also known as PLXDC2 is a 529 amino acid single-pass type I membrane protein containing one PSI domain and belonging to the plexin family. Localizing to membrane, TEM7R is expressed in endothelial cells of the stroma, as well as in limbs, lung buds, developing heart, spinal cord and dorsal root ganglia. TEM7R interacts with cortactin and may play a role in tumor angiogenesis. Existing as three alternatively spliced isoforms, the gene encoding TEM7R maps to human chromosome 10p12.31. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5 % of total DNA in cells and encodes nearly 1,200 genes. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman?s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.

Gene ID: 84898