Calsyntenin 1 antibody (AA 29-350)

Catalog No. ABIN7266048

Product Details anti-Calsyntenin 1 Antibody

Target: Calsyntenin 1 (CLSTN1)

Binding Specificity: AA 29-350

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calsyntenin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: CLSTN1 Rabbit pAb

Sequence: ARVNKHKPWL EPTYHGIVTE NDNTVLLDPP LIALDKDAPL RFAGEICGFK IHGQNVPFDA VVVDKSTGEG VIRSKEKLDC ELQKDYSFTI QAYDCGKGPD GTNVKKSHKA TVHIQVNDVN EYAPVFKEKS YKATVIEGKQ YDSILRVEAV DADCSPQFSQ ICSYEIITPD VPFTVDKDGY IKNTEKLNYG KEHQYKLTVT AYDCGKKRAT EDVLVKISIK PTCTPGWQGW NNRIEYEPGT GALAVFPNIH LETCDEPVAS VQATVELETS HIGKGCDRDT YSEKSLHRLC GAAAGTAELL PSPSGSLNWT MGLPTDNGHD SD

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 29-350 of human CLSTN1 (NP_055759.3).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Calsyntenin 1

Target: Calsyntenin 1 (CLSTN1)

Alternative Name: CLSTN1 (CLSTN1 Products)

Background: This gene is a member of the calsyntenin family, a subset of the cadherin superfamily. The encoded transmembrane protein, also known as alcadein-alpha, is thought to bind to kinesin-1 motors to mediate the axonal anterograde transport of certain types of vesicle. Amyloid precursor protein (APP) is trafficked via these vesicles and so this protein is being investigated to see how it might contribute to the mechanisms underlying Alzheimer's disease. Alternative splicing results in multiple transcript variants.,CLSTN1,ALC-ALPHA,CDHR12,CST-1,CSTN1,PIK3CD,XB31alpha,alcalpha1,alcalpha2,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CLSTN1

Molecular Weight: 108kDa/109kDa

Gene ID: 22883

UniProt: O94985