camsap1 antibody, si:dkey-157g20.3 antibody, PRO2405 antibody, bA100C15.1 antibody, 9530003A05Rik antibody, C77823 antibody, RGD1565022 antibody, calmodulin regulated spectrin associated protein 1 antibody, calmodulin regulated spectrin-associated protein 1b antibody, calmodulin regulated spectrin-associated protein 1 antibody, calmodulin regulated spectrin associated protein 1 S homeolog antibody, CAMSAP1 antibody, camsap1b antibody, Camsap1 antibody, camsap1.S antibody
Background
Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization. Specifically recognizes growing microtubule minus-ends and stabilizes microtubules. Acts on free microtubule minus-ends that are not capped by microtubule-nucleating proteins or other factors and protects microtubule minus-ends from depolymerization. In contrast to CAMSAP2 and CAMSAP3, tracks along the growing tips of minus-end microtubules without significantly affecting the polymerization rate: binds at the very tip of the microtubules minus-end and acts as a minus-end tracking protein (-TIP that dissociates from microtubules after allowing tubulin incorporation. Through interaction with spectrin may regulate neurite outgrowth.,CAMSAP1,Stem Cells,Neural Stem Cells,CAMSAP1