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PRUNE antibody (AA 201-300) (Biotin)

PRUNE Reactivity: Mouse WB, ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN717088
  • Target See all PRUNE Antibodies
    PRUNE (Prune Exopolyphosphatase (PRUNE))
    Binding Specificity
    • 14
    • 9
    • 8
    • 6
    • 5
    • 4
    • 1
    AA 201-300
    Reactivity
    • 37
    • 17
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 45
    • 6
    Rabbit
    Clonality
    • 47
    • 4
    Polyclonal
    Conjugate
    • 18
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRUNE antibody is conjugated to Biotin
    Application
    • 39
    • 23
    • 16
    • 13
    • 13
    • 13
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human DRES17
    Isotype
    IgG
    Top Product
    Discover our top product PRUNE Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    PRUNE (Prune Exopolyphosphatase (PRUNE))
    Alternative Name
    DRES17 (PRUNE Products)
    Synonyms
    PRUNE antibody, DRES-17 antibody, DRES17 antibody, HTCD37 antibody, 9230112O05Rik antibody, C130058A12 antibody, PRUNEM1 antibody, Prune-M1 antibody, prune exopolyphosphatase antibody, prune exopolyphosphatase 1 antibody, PRUNE1 antibody, Prune1 antibody
    Background

    Synonyms: DRES17, Drosophila-related expressed sequence 17, hprune, HTCD37, Prune homolog, PRUNE like protein, TcD37 homolog, PRUNE_HUMAN.

    Background: PRUNE, the human homologue of the Drosophila gene, is located in 1q21.3, a region highly amplified in human sarcomas, malignant tumours of mesenchymal origin. Human prune (h-prune), a phosphoesterase DHH family appertaining protein, physically interacts with nm23-H1, a metastasis suppressor gene. h-prune is involved in cellular motility and metastasis formation. Metastatic breast cancers were found to overexpress h-prune, h-prune was also found to be highly expressed in colorectal and pancreatic cancers. Hence h-prune is considered useful as a marker for tumor aggressiveness.

    Gene ID
    58497
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