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BTK antibody

BTK Reactivity: Human WB, IHC, IF Host: Rabbit Monoclonal unconjugated
Catalog No. ABIN7265950
  • Target See all BTK Antibodies
    BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
    Reactivity
    • 123
    • 79
    • 62
    • 12
    • 6
    • 4
    • 2
    Human
    Host
    • 141
    • 13
    Rabbit
    Clonality
    • 129
    • 26
    Monoclonal
    Conjugate
    • 66
    • 12
    • 9
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    This BTK antibody is un-conjugated
    Application
    • 103
    • 59
    • 40
    • 40
    • 37
    • 18
    • 17
    • 17
    • 10
    • 10
    • 10
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Purpose
    BTK Rabbit mAb
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Monoclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    A synthesized peptide derived from human BTK
    Isotype
    IgG
    Top Product
    Discover our top product BTK Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
    Alternative Name
    BTK (BTK Products)
    Background
    The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013],AGMX1,AT,ATK,BPK,IMD1,PSCTK1,XLA,BTK,Apoptosis,B Cell Receptor Signaling Pathway,Cell Biology & Developmental Biology,Cell Intrinsic Innate Immunity Signaling Pathway,Immunology & Inflammation,Innate Immunity_TLR Signaling,Kinase,Kinase_Tyrosine kinases,Protein phosphorylation,Signal Transduction,Toll-like Receptor Signaling Pathway,BTK
    Molecular Weight
    76kDa
    Gene ID
    695
    UniProt
    Q06187
    Pathways
    Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, BCR Signaling
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